Meaning of life If we dumped out a collection of stuff onto a table, you'd be able to meaningfully sort through it on the basis of what might be useful to you at a present or future date.
We assess the value of things, people (et cetera).
If you were heavily depressed, to the point that you couldn't even look at the stuff I dumped out on to the table, then maybe there has been a significant loss in the capacity to find value in those things.
Depressed and anxious people are likely to say that "life has no meaning." Maybe there are perceived barriers to acquiring a meaningful state of being for many people.
I often think that if I only had tons of money, life would be more enjoyable, since the tedium and unpleasantness of work could be dispensed with in pursuit of other options (meaningful kinds of work).