The guy knows shit about it, he is an oncologist. — Olivier5
He is a cancer drug and health policy researcher. He also studies the financial conflicts in drug approvals.
What is unfair I think, would be to share a political cartoon as if it was the informed opinion of a specialist of the field being discussed. This is what you are doing with Prasad's cartoonish views. — Olivier5
I'm sure his academic articles on oncology — Olivier5
I never gagged anyone. — Olivier5
don't spread the unhelpful anti-science rhetoric of folks with an easily discernable political bias and no qualification in immunology. Thank you very much. — Olivier5
I don't peddle the personal political opinions of some random folks — Olivier5
nor any version of immunology — Olivier5
philosophy forum... — Olivier5
Which is a ridiculous, totally fake idea about modern science. — Olivier5
He doesn't fit the "no conflict of interest" criteria, period. — Olivier5
Scientists can comment all they want on politics — Olivier5
in his case his statements show a strong political bias towards the right — Olivier5
That is what I am saying too: it was anti-science rhetoric. — Olivier5
He is mentioning his books in a lot of his posts... :-) — Olivier5
Saying that Covid is the end of progressivism is not an overt political statement? — Olivier5
Prasad concludes that "sadly, there are few scientists left". Words have a meaning, Isaac. I for one think there are many scientists left. Do you think otherwise? — Olivier5
I am saying rather that you are spreading the anti-science rhetoric of a heavily politicized pundit about Covid — Olivier5
But you didn't do so, probably because you trusted him enough. — Olivier5
In short, what are your standards? — Olivier5
evidence should come from suitably qualified experts in the appropriate field who have no discoverable conflict of interest or pre-existing bias directly favouring one result — Isaac
I am saying that ANTI-SCIENCE RHETORIC IS NOT HELPFUL. — Olivier5
It's mainly about discourse outside of scientific outlets — Olivier5
it's about what to do against covid — Olivier5
you HAVE spread the unhelpful anti-science rhetoric of a person with an easily discernable political bias. — Olivier5
they are not about 'actual scientific debate', most of the times. — Olivier5
After that, I got a series of warnings from professional contacts and others, asking me if I had aligned with Donald Trump
there is a lot of anger, and a lot of the scientific discourse has become very acrimonious and even personal… It’s beginning to feel like open discussion is being stifled
The covid-19 pandemic has accentuated an erosion in civility in academic discourse...in professional media — literally the first fucking line
Lenzer and Brownlee were in turn personally criticised after their essay was published, not merely on social media, but more importantly in communications to organizations to which they belong and publications for which they had previously written
Words have a meaning. — Olivier5
Indeed, it's rhetoric. But it is a type of rhetoric that undermines public trust in science. — Olivier5
To say that there are knee-jerk reactions on twitter or in the press about certain opinions published by scientists — Olivier5
Even a polemist such as yourself should keep a sense of proportion. To say that there are knee-jerk reactions on twitter or in the press about certain opinions published by scientists, is quite different from saying: "sadly, there are few scientists left". — Olivier5
Yes. In fact spreading manufactured doubt in such a time is criminal. It kills people, and I dare say our good friend Isaac here is close to murder.
Of course it makes for more interesting conversations. I guess Russian roulette is more interesting than casino roulette too. Spices up the game... — Olivier5
I looked Mr Prasad up. His blog is poorly written, full of platitudes, and, yeah, paranoid. — Olivier5
The first crux of the public communication failure is to ask why, when we hear of a novel adverse event, is the reaction of so many experts to downplay or trivialize the risk? Why construct minimizing memes when you have not even gathered all the relevant facts? ...Either one must embrace all vaccines for all indications for all ages, or one can be lumped with the other extreme. They favor universal child vaccination of SARS-CoV-2 via an EUA, even before they have the data for that claim. They were quick to embrace vaccination for pregnant woman prior to appropriate trials establishing safety. Suppressing critical thinking to extol vaccines is also wrong
...science means being able to say that mRNA vaccines are terrific; their benefit to Americans in massive. The J&J vaccine also has an important role, but that role is uncertain in women under 65, and for that subgroup the EUA may still be rescinded. A true scientist navigates these troubled waters and does not take reflexive extremes. Sadly, there are few scientists left. — https://www.medpagetoday.com/infectiousdisease/covid19vaccine/92413
even if his argument is a good one, that he represents a minority view. Do you agree? If so, my question to you is: why highlight the minority view -- or, better: why is his view more convincing than the majority's/consensus? Assuming it's split down the middle, and there's good evidence on either side -- which is plausible -- do you have any insight into why you would gravitate towards this interpretation more than the other? — Xtrix
85% of vaccine clinical trials are sponsored by vaccine manufacturers and non-industry trials are over four times more likely to report negative or mixed findings than industry-sponsored trials — Manzoli L, Flacco ME, D’Addario M, et al. Non-publication and delayed publication of randomized trials on vaccines: survey. BMJ2014
industry-sponsored economic evaluation of vaccination scored worse in methodological appropriateness than a comparable non-industry evaluation — Beutels P. Potential conflicts of interest in vaccine economics research: a commentary with a case study of pneumococcal conjugate vaccination. Vaccine2004
a principal investigator of HPV vaccine trials for Merck and GlaxoSmithKline agreed that “It seemed very odd to be mandating something for which 95 percent of infections never amount to anything” Further, a recent review showed that design problems in the HPV vaccine trials, most of which were led by academics but sponsored by industry, made it difficult to evaluate the extent to which the vaccine prevented cervical cancer — as above
when you say reasonable alternatives exist, what are you referring to? — Xtrix
when taking into account the benefits, are you including the benefits to others as well, or just to the individual (for example, the "young/healthy" individual)? — Xtrix
when referring to examples of pharmaceutical companies hiding safety information, etc., are you referring specifically to COVID vaccines or other products? — Xtrix
Pfizer’s 92-page report didn’t mention the 3410 “suspected covid-19” cases. Nor did its publication in the New England Journal of Medicine. Nor did any of the reports on Moderna’s vaccine. The only source that appears to have reported it is FDA’s review of Pfizer’s vaccine. — Pfizer’s 92-page report didn’t mention the 3410 “suspected covid-19” cases. Nor did its publication in the New England Journal of Medicine. Nor did any of the reports on Moderna’s vaccine. The only source that appears to have reported it is FDA’s review of Pfizer’s vaccine.
Data from the biodistribution studies submitted by Moderna and Pfizer suggests that the vaccines distribute widely in the body, including to the liver, brain, heart, lung, adrenals, ovaries, and testes, among many other tissues. However these were not studies of the currently authorized products: Pfizer’s BNT162b2, Moderna’s mRNA-1273, or Janssen’s Ad26.COV2.S.34–36 Instead of presenting novel biodistribution studies of the COVID-19 vaccine formulations, sponsors presented substitute studies to FDA for an EUA during the pandemic. 34–36
All attention has focused on the dramatic efficacy results: Pfizer reported 170 PCR confirmed covid-19 cases, split 8 to 162 between vaccine and placebo groups. But these numbers were dwarfed by a category of disease called “suspected covid-19”—those with symptomatic covid-19 that were not PCR confirmed. According to FDA’s report on Pfizer’s vaccine, there were “3410 total cases of suspected, but unconfirmed covid-19 in the overall study population, 1594 occurred in the vaccine group vs. 1816 in the placebo group.”
With 20 times more suspected than confirmed cases, this category of disease cannot be ignored simply because there was no positive PCR test result. Indeed this makes it all the more urgent to understand. A rough estimate of vaccine efficacy against developing covid-19 symptoms, with or without a positive PCR test result, would be a relative risk reduction of 19%
I say all of this in anticipation. I would expect your evidence to demonstrate either (a) or (b). — Xtrix
For adults, the benefits of COVID-19 vaccination are enormous, while for children, they are relatively minor. Rare side effects from adult COVID-19 vaccination are unlikely to lead to future vaccine hesitancy whose public health impact could be comparable to the benefits of the adult COVID-19 vaccination program itself. But accelerated mass child vaccination under EUA — perhaps even spurred by school mandates and “vaccine passports” — presents a different balance of risks and benefits. Rare adverse events really could prove to be the most durable public health legacy of an EUA for child COVID-19 vaccines. — https://blogs.bmj.com/bmj/2021/05/07/covid-vaccines-for-children-should-not-get-emergency-use-authorization/
Given all these considerations, the assertion that vaccinating children against SARS-CoV-2 will protect adults remains hypothetical. Even if we were to assume this protection does exist, the number of children that would need to be vaccinated to protect just one adult from a bout of severe covid-19—considering the low transmission rates, the high proportion of children already being post-covid, and most adults being vaccinated or post-covid—would be extraordinarily high. Moreover, this number would likely compare unfavourably to the number of children that would be harmed, including for rare serious events. — https://blogs.bmj.com/bmj/2021/07/13/covid-19-vaccines-for-children-hypothetical-benefits-to-adults-do-not-outweigh-risks-to-children/
what of the millions who have no yet had COVID? — Xtrix
But please link to the BMJ too. — Xtrix
I believe you have agreed with this, which is why the rest is a bit puzzling to me. — Xtrix
The alternative solution, in this case, is natural immunity -- which one must contract COVID in order to obtain.
This assumes (1) that getting COVID is less risky for the individual than taking the vaccine — Xtrix
...and (2) that there aren't external factors to consider, including the spread. — Xtrix
Professor Paul Hunter, from the University of East Anglia, who said it was 'absolutely inevitable' new variants that can escape the protection of the vaccine will emerge in the future.
Prof Pollard told the APPG that herd immunity is 'not a possibility' with the current Delta variant.
He referred to the idea as 'mythical' and warned that a vaccine programme should not be built around the idea of achieving it.
He predicted that the next thing may be 'a variant which is perhaps even better at transmitting in vaccinated populations', adding that that was 'even more of a reason not to be making a vaccine programme around herd immunity'.
With kids, they’re not going to stop transmission, they won’t stop escape variants, nothing is. It is about the risk to the child themselves. Vaccine escape is inevitable and I think that it adds to the argument not to have a blanket rollout of the vaccine to children aged 12-15 because I think that will minimise that. — Dr Ruchi Sinha - All-Party Parliamentary Group on Coronavirus
The analogy wasn't strictly about bias and motives, really, but about why people end up saying the things they do and interpreting the evidence the way they do. — Xtrix
True. But this can be claimed about nearly any dialogue whatsoever, no? — Xtrix
I believe every word of it, and suspected something like that -- although I had assumed more the sciences than English. — Xtrix
I'm more than willing. — Xtrix
With this issue, it's similar to claims about a stolen election. Do you make the same argument there, as well? — Xtrix
Nothing said here alters my view in the slightest. The development and launch of the COVID-19 vaccines is a triumph of science and public medicine — Wayfarer
mandates are legitimate. They "check out" when you look at the decision more closely, follow the logic, listen to the experts, and check their evidence -- at least it does for me. It's very convincing to me, and so far from what you've written, I'm simply not persuaded otherwise. I have problems not with your conclusion only, which you accuse me of, but your assumptions, your logic, the references you've cited, and your interpretation of the evidence. I think you're making several mistakes. — Xtrix
I've offered analogies to help flush out where I think you're making errors. I think the comparison to creationists is a good one -- not because I think you're being almost completely irrational the way they are, but because it's an example we can both agree on, and which my hope was would allow you to see some mistakes I thought you were making. — Xtrix
Let me get more to the matter at hand and hopefully start anew: — Xtrix
they "check out" when you look at the decision more closely, follow the logic, listen to the experts, and check their evidence — Xtrix
What exactly is your objection to it, fundamentally? — Xtrix
Should a state never be allowed to mandate anything? Should a state be allowed to create laws and to enforce those laws? — Xtrix
What makes a law "just" or legitimate? — Xtrix
What is the purpose of a state or a government, in your view? — Xtrix
I also pointed to evidence of this: the level of resistance is correlated with "redder" counties (those that went increasingly strongly for Donald Trump). Do you assume that's an accident or coincidence? I don't. — Xtrix
You should not take it as an accusation, it's more a warning, in the sense that your mind is not totally gone yet I think. You can still pull it together if you try. It's also a way to flag to other posters that there might be some mental toxicity involved there, in case they haven't noticed already. — Olivier5
Well, so sorry I didn't manage to convince you then. — Olivier5
Paranoids are very hard to convince of their own paranoia, as you must know. In fact it is most of times impossible to do so. — Olivier5
That is not true. You genuinely could not understand at first the very simple idea of rewarding pharmaceuticals for their good work on vaccines. And that's because in your mind they are inherently evil. — Olivier5
My question is: why did the idea seem so counterintuitive to you at first? Why did you initially (and during many posts) reject this very simple idea, that even the pharmaceuticals need incentives to do the right thing? — Olivier5
So what was so hard to understand then? What were all these "WTF" and other expressions of disbelief for, in the past dozen posts since I introduced this now seemingly agreeable idea? Why did it take you so much time to get your head around it? — Olivier5
disgusting, creepy paranoid shit — Olivier5 — Isaac
I’m talking about— and have been from the beginning — the United States. — Xtrix
Your views are enough. — Xtrix
CDC said just what I said: the technology has been around for decades. I’ll quote them again— from your source: — Xtrix
The vaccines are safe and effective. — Xtrix
Mandates are completely legal and justified — Xtrix
If we make use of their vaccines, we have to pay them for it, thus rewarding the good work done and incentivizing the future production of safe and effective vaccines. That's agreed then? — Olivier5
So where have I suggested we shouldn't make use of the vaccine? — Isaac
disgusting, creepy paranoid shit — Olivier5
I am saying that not using an effective vaccine would be irrational, counterproductive and perverse both in long term and short term. — Olivier5
I didn't say that anyone rejecting it is crazy, — Olivier5
Since the vaccines are effective, it is in our short-term interest to buy them anyway. Long-term, it incentivizes pharmaceutical to produce more safe and effective vaccines in the future.
If on the other hand we say: "these people are inherently evil, hence we should not buy their safe and effective vaccines, or only buy as few of them as we possibly can", we shoot ourselves in the foot by depriving ourselves of these effective and safe vaccines, and by giving pharmaceuticals no incentives to produce more safe and effective vaccines in the future. So this would be perverse. — Olivier5
why you think my view 'paranoid'. — Isaac
Because of its essentialist and absolutist angles. — Olivier5
a non-absolutist (ie relativist) and non-essentialist (ie pragmatic, result-oriented) view of dishonest behaviors within pharmaceuticals would be to say something like this: "pharmaceuticals can do bad things (eg lobby for a dangerous drug) and good things (eg develop safe and effective vaccines). We should try and discourage them to do the former by using the law to its fullest extent against them when they do bad things, and also encourage them to do the latter, by purchasing their vaccines when they are safe and effective. — Olivier5
I said they should be rewarded for doing the right thing. — Olivier5
Nope, you encourage them to do the right thing. — Olivier5
"pharmaceuticals can do bad things (eg lobby for a dangerous drug) and good things (eg develop safe and effective vaccines). We should try and discourage them to do the former (via the law) and encourage them to do the latter, by purchasing their vaccines when they are safe and effective. — Olivier5
