Tastes and preferences. Namely, as mentioned in the OP, if we reduce matters of what gives one meaning in life or purpose to a matter of taste or personal whim, then haven't we idiotized the issue of what gives one meaning in life to a simple matter of what I like best or dislike most? — Wallows
Only if epistemology is premised upon a hard object-subject distinction. Or put equivalently, that one's epistemology is based upon the correspondence theory of truth, or alternatively, that pre-existing truth is interpreted as being discovered rather than presently constructed by the observer, whereby their preferences and decision-making are considered irrelevant to the truth they obtained.
Once the correspondence theory of truth is rejected, epistemological scepticism is transformed into ethical and aesthetic preferences.
For example, consider the so called epistemological problem of other minds. According to the correspondence theory of truth, either other minds exist or other minds do not exist and their ontological status is independent of the way human behaviour is judged by an observer. This leads to sceptical doubt , the problem of individuality, the hard-problem of consciousness etc.
On the other hand, suppose the "truth maker" concerning the existence of other minds, is viewed more holistically as being as much a function of an observer's perceptual relationship to the entity he is observing. According to this anti-realist account, an observer's conception of other minds is as much an account of his personal preferences that guide his perceptual and cognitive actions than it is the behavioural data he is viewing.
So in short, if correspondence theory is rejected, then preferences are epistemologically relevant.