On the nature of happiness, misery, and peace. The Five Levels of Attachment deal with this nicely, I think, with respect to attachment to things, people, ideas, and even identity/ego. Zero attachment is difficult to achieve, because some of it is biologically driven (e.g. bond between parent and child). As much as you strive to artificially detach from the world and life, your biological needs will cause at least some discomfort, if not misery, and you will be giving up on many of the positives. Zero attachment with regard to identity/ego is likely achievable - once you are able to observe the attachment you've built up throughout your lifetime - but not necessarily desirable, with regard to the experience of pleasure and peace/contentment. The author suggests that there is a healthy level of attachment, where you view your life and identity more as a work of art, rather than a set of absolute beliefs and ideas. This allows you to form softer attachments that are more malleable and flowing, open to change. Accepting your human biological attachments and emotions will limit (or even eliminate, if you stop seeing grief and other 'negative' emotions as bad things, with all of the negative self-talk attached) the amount of suffering in your life.