The irreducibility of phenomenal experiences does not refute physicalism. But if the reason something cannot be explained is not about ontology but about limits in explanation then I don't think that is an argument against physicalism. If information processing is a physical thing based on particular architectures then it is plausible that there are limits on what it can explain just like how a cat brain cannot explain things a human brain can. You might not expect some kind of machine learning architecture to explain itself without the right kind of structure either. If a physicalist thinks that our brain does all the information processing then if there are plausible reasons to suggest that there are limits on the kinds of reports a brain can generate about the information it processes or things it does, then it might seem reasonable from a physicalist point of view to say that they believe everything is physical - because thats what all the scientific evidence suggests - but my brain architecture is just physically incapable of producing the kinds of reductions, explanations or descriptions that you might want and perhaps should not be capable of doing that if it needs to be representing veridical information about the outside world.