I was thinking about the effect THC has on patients with severe Parkinson's disease. Studies have shown that they regain a lot of control over their muscles and movements after taking it. By my observations, it might be that Parkinson's disease disjoints the nerve signals so that the intention to move and the movement gets fractured and overlap. So after my observations, the separation of intention to move and the movement itself might be why patients with Parkinson's disease experience an improvement in movement, since the overlapping and disjointed nerve signals separate so far between intention and movement that it no longer overlaps as much as without it. — Christoffer
Wow! Keep thinking Christoffer! If you wish you can read thru my mostly emotional posts in my history but let me just touch on a few things you are pondering and see what you think.
You are the first who I have seen focusing on the effects of the THC which because of the Reefer Madness bs has been summarily dismissed for the CBD and it's antinflamitory affects. The path you are on is the one less travelled, one which you are ahead of me on and that is impressive to me seeing as how long I have been on this pursuit measures in the decades. My Dad passed away last summer from complications of Parkinson's disease and as an advocate for Cannabis, I thought a lot about what I could have done for him had he lived in my state. 10+ years into his disease he was as sharp mentally as he ever was. I listened to him as he would tell me his struggles as he became confined to a nursing home. When we would eat, his shaking would be impacted to the degree that 10% of what he started with made it to his mouth. As a practicing Mormon, it was the best I could do to get him to drink caffeine to help control the tremors. Caffeine helped but made him "think" about the next in life and he didn't want to think more about the inevitable, which is when I stopped pushing the caffeine. But Cannabis...to have the fresh, never explored, Endocannabinoid receptor system already in place in the patient? I will be accused of seeing Cannabis as a panacea and at times I let it stifle my words but not in my actions.
As you look for the effects on Parkinson's, I am in active pursuit of the impact Cannabis can have not just treating the symptoms of Alzheimer's dis-ease but in using Cannabis profolactictly, to keep the plaque from ever forming.
Part of my theory is based on the idea that if someone is administered a concentrated dose of Cannabis within 48 hrs of an event that has a history of producing traumatic result, it can keep the nueropathways from holding onto the stress and has the potential to reduce the chances of PTS in soldiers and maybe onto the general population at some point.
Whether it is Parkinson's and the muscle memory I think you are speaking of which has been shown to be overcome with music that the patient knows the dance beat to with no shuffle or Parkinson's instability. My thought is that music crosses both sides of the brain barrier and muscles have enough memory within them, that somehow that connection is stable again.
Just before I go, when I talk about muscle memory, I use the analogy of a coiled garden hose. If you wrap the hose the right way, the way it knows, it coils easily. But when you try to reverse coil the hose, you are likely in for a fight to keep it from getting tangled up in it's efforts to return to it's original coil. That which you are fighting to reverse coil is similar to the 'memory' that muscles have and in a Parkinson's patient I wonder if you are onto something with Cannabis, specifically THC, and tapping into the muscle memory in the way music does.
Keep thinking Christoffer and keep posting your ideas for we are here, standing beside you, even if it doesn't always feel that way. The impact we have on one life at a time adds up but maybe more importantly is when we can help those we love most in life.
:sparkle:
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