Some people can be psychopaths due to a gene. — I like sushi
The underlying molecular mechanisms have remained unknown but several previous studies suggest that abnormal glucose metabolism and opioidergic neurotransmission contribute to violent offending and psychopathy. Here we show using iPSC-derived cortical neurons and astrocytes from six incarcerated extremely antisocial and violent offenders, three nonpsychopathic individuals with substance abuse, and six healthy controls that there are robust alterations in the expression of several genes and immune response-related molecular pathways which were specific for psychopathy. In neurons, psychopathy was associated with marked upregulation of RPL10P9 and ZNF132, and downregulation of CDH5 and OPRD1. In astrocytes, RPL10P9 and MT-RNR2 were upregulated. Expression of aforementioned genes explained 30–92% of the variance of psychopathic symptoms. The gene expression findings were confirmed with qPCR.
In conclusion, expression of ZNF132 in neurons and RPL10P9 in both neurons and astrocytes is markedly abnormal among habitually violent offenders and these findings are strongly associated with the degree of psychopathic symptoms. The changes in protein levels observed here point to alteration in insulin sensitivity and glucose metabolism, and previous literature has shown that abnormal glucose metabolism is the only predictor for violent crimes which can surpass the accuracy of PCL-R [35]. We also observed changes in the opioid system, which has been shown to support prosocial functions, such as empathy, among humans and nonhuman primates [12, 13, 37, 38].
The fact that there are genes that correspond to psychopathic behaviour is OLD news. Very old news. — I like sushi
You can do the research or keep spouting crap that will likely get you removed from this forum. Your choice. — I like sushi
I guess I shouldn’t be surprised when the same person calls science ‘dogmatic’. — I like sushi
Ask god maybe? It’s clear you cannot read or simply don’t understand what you’re reading (which amount the same thing). I won’t be responding any more to anything you say - other than by reporting it to mods — I like sushi
My point was that people can suddenly be depression even though their life has been perfectly fine (including childhood). — I like sushi
What does "run in the family" then but inherited genes? This is a question from me.Already before they were considered psychopathy was thought to "run in the family". Which it does. But not because of genes. — EugeneW
What's against taking drugs? — EugeneW
I read somewhere that there are languages which use the same word for "weakness" and "strength." Can't remember the source or which languages. It makes sense to me that our weaknesses are also our strengths. — T Clark
Stephen says he was beaten "a great deal" while attending prep school until the age of 13. "I think in my last year I was probably beaten every day, because I was a very bad boy.
"People think, 'No wonder Stephen Fry is such a completely screwed up individual!' I don't know whether that is true, as I am sure I would have been screwed up wherever I had been."
It is not simply about being beaten or abused. — I like sushi
I personally believe it is a lack of trauma that is more damaging to the psyche than individual instances in childhood amounting to little more than ‘growing up’ in a world that is not exactly safe. — I like sushi
I just get annoyed when people think people always get depressed ‘for a reason’ when it is simply brain chemistry just going awry. — I like sushi
Is my condition actually an illness, or is it an adaptation, really?
Emotional Intelligence (Ability Model):
1.Perceiving emotions – the ability to detect and decipher emotions in faces, pictures, voices, and cultural artifacts—including the ability to identify one's own emotions. Perceiving emotions represents a basic aspect of emotional intelligence, as it makes all other processing of emotional information possible.
2. Using emotions – the ability to harness emotions to facilitate various cognitive activities, such as thinking and problem-solving. The emotionally intelligent person can capitalize fully upon his or her changing moods in order to best fit the task at hand.
3. Understanding emotions – the ability to comprehend emotion language and to appreciate complicated relationships among emotions. For example, understanding emotions encompasses the ability to be sensitive to slight variations between emotions, and the ability to recognize and describe how emotions evolve over time.
4. Managing emotions – the ability to regulate emotions in both ourselves and in others. Therefore, the emotionally intelligent person can harness emotions, even negative ones, and manage them to achieve intended goals. — Wikipedia
because I am somehow sick of severe depression — javi2541997
I would never consume any kind of drug (or alcohol) no matter what are the conditions. I prefer to be prone to suicide and be pride of who I am. I know it sounds crazy (I do not care about that either). — ithinkthereforeidontgiveaf
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