But some suspect it will be even lower, possibly lower than seasonal flu. Dr. John P. A. Ioannidis Recently wrote: — NOS4A2
What a complete idiot; can't believe this guy is correlated with the word "statistics". That's academia for you.
His reasoning is completely preposterous.
After explaining why sampling bias creates large uncertainties, which is true, that without good estimates of the infection fatality rate, no optimum strategy can be constructed. True. An honest intellectual would have pointed out why it was so critical to contain as effectively as possible during the initial outbreak to buy time to get good information to make good decisions.
But, either due to being a dishonest intellectual or then just a complete idiot, he does not want to inform his readers that people in charge completely dropped the ball during the initial phase where containment was still possible to either contain or at least significantly slow.
He really, really wants to criticize people who don't have an optimistic reading of the numbers, which he himself goes to some length to explain that there's not enough information to get a good estimate on way or another -- but insists on emphasizing only a rosy reading.
This leads up to his key premise which is as follows:
The most valuable piece of information for answering those questions would be to know the current prevalence of the infection in a random sample of a population and to repeat this exercise at regular time intervals to estimate the incidence of new infections. Sadly, that’s information we don’t have. — John Ioannidis
From this premise the reasonable conclusion is that sort of random testing should be carried out! so that it goes from being information we don't have to information we have. That should then be the end of his reasoning line: if we want better decisions we need better data which will require more testing capability as well as randomized testing. Another example of things that can't be done early on when testing is outsourced to a crony who then does a crappy job.
Instead of informing his readers that the Trump administration does have the power to do this, and therefore should do it, he instead criticizes people for "preparing for the worst scenario".
In the absence of data, prepare-for-the-worst reasoning leads to extreme measures of social distancing and lockdowns. Unfortunately, we do not know if these measures work. — John Ioannidis
Is his next sentence. What the hell is this? Most measures of social distancing are uncontroversial in that they work.
Epidemiologists, which this dufous apparently is, all agree social distancing measures work at reducing transmission rates. "Shelter in place" obviously works at reducing infection rates.
By focusing on one edge case of schools, where there is room for some debate, doesn't cast shade on all the other extreme measures of self-isolation and large scale quarantines. This is just completely dishonest argumentation to imply all social distancing measures have the same uncertainty as school closings; however, a numerical model recently leaked does show school closing as being effective, so, in order to keep "the uncertainty is the same" perspective he would need to at least provide a numerical model showing school closings are counter productive, which he doesn't because he's lazy and stupid.
School closures, for example, may reduce transmission rates. But they may also backfire if children socialize anyhow, if school closure leads children to spend more time with susceptible elderly family members, if children at home disrupt their parents ability to work, and more. School closures may also diminish the chances of developing herd immunity in an age group that is spared serious disease. — John Ioannidis
Maybe, maybe, maybe, maybe.
This is simply wishful thinking analysis.
The expression "Hope for the best, prepare for the worst" he basically wants to change to "Hope for the best, and also prepare the best".
It's completely reasonable to prepare for a worst case scenario if the Trump administration doesn't carry out the randomized testing that the author wants. That's the reasonable conclusions to the "room for doubt" that he brings up: "The administration is completely incompetent, the infection rate is out of control and not tracked correctly, we don't know what will happen, policy reactions will not be optimum leading to high second order risks in terms of economic and social disruption fallout."
Yes, a rosy scenario is still possible, that "it's not so bad".
But a black scenario is also still possible. Health-care workers are disproportionately affected, have much higher infection rates due to close proximity and starting to run out of protective gear already in the first weeks of the crisis, and death rates and "just them older doctors" we should care about dying more than is needed, as they have a lot of experienced their loss represents long term damage to the health system. The capacity of the health care system is not constant through a "acute" overload, but could be significantly damaged leading to a protracted under capacity to deal with other disease anyways; the author does not mention the benefits he points out in his rosy scenario are not assured, but also unknown, since the author is unable to think critically. In an overloaded scenario many more young people may die without treatment; this number is also unknown, extrapolating from the cruise ship numbers is not a valid proxy to the "run wild" hypothesis. Letting it run rampant also maximizes the probability and also evolutionary pressure to mutate into something worse. Long term damage to lungs and other organs is also among the things unknown at this point, especially without treatment which would result from no social distancing. Also critically, re-infection, due to losing immunity in a relatively short time or then mutation, is also unknown; so, letting the virus run rampant cannot be assumed to provide everyone immunity, and the virus may come back as a second wave pandemic putting us back to square one but with a severely damaged health system and maybe a worse virus to deal with.
That the black scenarios can't be ruled out is why all the measures being seen are taken by every country that has an exponential outbreak, and strict quarantine and travel restriction are being put in place by countries that do, as another social distancing measures, and countries that don't in order to carry out the containment strategy competently to buy time to prepare and learn from failed policy cases; including now Trump! is doing some extreme social distancing like stopping planes, and various states individually as well are going more extreme to fill the policy gaps!
The idea of "letting it run its course" was investigated, governments put competent statisticians on the job; no country would be stopping nearly all economic activity if rosy scenarios weren't essentially all ruled out at this point. The author doesn't mention this, because the author wittingly or unwittingly, wants his readers to imagine that government's just listen to lefty snowflake twitter users to make decisions.
Wha't the reasoning for attacking Trump's own decisions now of taking things "super seriously", indeed deciding to have taken it super seriously from the beginning and now implementing severe measures? That the "libs got so loud that Trump was forced to act on the left's snowflake delusions." It's a crazy line of argument to imagine that the left is actually in charge, somehow, now that the stock market it tanking and Trump is no longer "sticking it to the left" by downplaying the pandemic as "just a flu".
It's the most stupendous feet of double think that I have so far witnessed in the political scene.
If you want to criticize the reaction, criticize the administration that is currently in charge of the reaction.
If you want to criticize the lack of data needed to create a optimum strategy in terms of "life lost from the virus" and "life lost due to reactive and overdone policies affecting the economy", then criticize the administration for A. abandoning effective containment and contact tracing so that little time was bought to figure out the information needed B. fumbling the layup "make tests available" to do random sampling as well as track symptomatic cases and C. not doing random sampling testing even now to have a clear idea of what the situation is now.